Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676713 | 0.81 | ALDH1A1 (0.51) | ALDH1A1GFERDYRK1AAPLNRCA12 | |
| SCHEMBL1571408 | 0.80 | APLNR (0.43) | APLNRESR1CYP19A1ESR2CA12 | |
| SCHEMBL590943 | 0.78 | APLNR (0.63) | ALDH1A1GFERDYRK1AAPLNRCA12 | |
| SCHEMBL6804542 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GFERDYRK1AAPLNRESR1 | |
| SCHEMBL4510419 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GFERDYRK1AAPLNRCA12 | |
| SCHEMBL2075977 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GFERDYRK1AAPLNRCA12 | |
| SCHEMBL12516104 | 0.77 | APLNR (0.41) | APLNRESR1CYP19A1ESR2CA12 | |
| SCHEMBL10607506 | 0.76 | DYRK1A (0.49) | ALDH1A1GFERDYRK1AAPLNRIDO1 | |
| SCHEMBL27865105 | 0.76 | POLB (0.57) | ALDH1A1GFERESR1CYP19A1ESR2 | |
| SCHEMBL489792 | 0.76 | ALDH1A1 (0.47) | ALDH1A1GFERDYRK1AAPLNRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668861-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | Inflazome Limited (IE) | 2020-06-24 | — | — | EP | disclosed |
| EP-3661925-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | Inflazome Limited (IE) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019034686-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019008025-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-01-10 | — | — | WO | disclosed |
| EP-1232164-A1 | PRE-CURSOR FOR RADIODIAGNOSTIC AGENTS AND THE PRODUCTION THEREOF | ABX Advanced Biochemical Compounds Biomedizinische Forschungsreagenzien GmbH (DE) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001027122-A1 | PRE-CURSOR FOR RADIODIAGNOSTIC AGENTS AND THE PRODUCTION THEREOF | ABX ADVANCED BIOCHEMICAL COMPOUNDS BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) | 2001-04-19 | — | — | WO | disclosed |