Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401311 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GFERDYRK1AHTR2AHTR2C | |
| SCHEMBL9676713 | 0.83 | ALDH1A1 (0.51) | ALDH1A1GFERDYRK1AAPLNRHTR2A | |
| SCHEMBL30486651 | 0.81 | APLNR (0.46) | APLNRHTR2AHTR2CCA12CA1 | |
| SCHEMBL3484107 | 0.81 | APLNR (0.46) | APLNRHTR2AHTR2CCA12CA1 | |
| SCHEMBL3527192 | 0.81 | APLNR (0.46) | APLNRHTR2AHTR2CCA12CA1 | |
| SCHEMBL4510419 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GFERDYRK1AAPLNRHTR2A | |
| SCHEMBL6603605 | 0.79 | APLNR (0.44) | APLNRHTR2AHTR2CCA12CA1 | |
| SCHEMBL8640683 | 0.79 | IDO1 (0.48) | APLNRHTR2AHTR2CCA12CA1 | |
| SCHEMBL590943 | 0.79 | APLNR (0.63) | ALDH1A1GFERDYRK1AAPLNRHTR2A | |
| SCHEMBL20446477 | 0.79 | HTR2B (0.50) | APLNRHTR2AHTR2CIDO1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730892-B2 | Homoallylamines as formaldehyde-responsive triggers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-10730892-B2 | Homoallylamines as formaldehyde-responsive triggers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-02 | — | — | US | disclosed |
| WO-2017034927-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-02 | — | — | WO | disclosed |
| EP-2831054-B1 | IMPROVED PROCESS FOR PRODUCING (S)-EQUOL | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| US-9051291-B2 | Process for producing (S)-equol | DR. REDDY'S LABORATORIES LIMITED (IN) | 2015-06-09 | — | — | US | disclosed |
| US-20150057456-A1 | PROCESS FOR PRODUCING (S)-EQUOL | DR. REDDY'S LABORATORIES LIMITED (IN) | 2015-02-26 | — | — | US | disclosed |
| EP-2831054-A1 | IMPROVED PROCESS FOR PRODUCING (S)-EQUOL | Dr. Reddy's Laboratories Ltd. (IN) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013144857-A1 | IMPROVED PROCESS FOR PRODUCING (S)-EQUOL | DR. REDDY'S LABORATORIES LIMITED (IN) | 2013-10-03 | — | — | WO | disclosed |
| US-20040043994-A1 | Gem-substituted alpha v beta 3 antagonists | PHARMACIA CORPORATION | 2004-03-04 | — | — | US | disclosed |
| EP-1313705-A1 | GEM-SUBSTITUTED ALPHA V BETA 3 INTEGRIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6531494-B1 | Gem-substituted αvβ3 antagonists | PHARMACIA CORPORATION | 2003-03-11 | — | — | US | disclosed |
| WO-2002018340-A1 | GEM-SUBSTITUTED α v β 3 INTEGRIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215773-A1 | HOMOALLYLAMINES AS FORMALDEHYDE-RESPONSIVE TRIGGERS | HCAR2, HCAR1, HTR2A | ALDH1A1 1031/4885GFER 213/4885DYRK1A 792/4885 |
| US-20150057456-A1 | PROCESS FOR PRODUCING (S)-EQUOL | UGT1A7, CYP8B1, CYP2A7 | ALDH1A1 489/4885GFER 1462/4885DYRK1A 4541/4885 |
| US-20040043994-A1 | Gem-substituted alpha v beta 3 antagonists | CACNG5, ITGAV, ITGA5 | ALDH1A1 2319/4885GFER 3956/4885DYRK1A 4623/4885 |
| US-10730892-B2 | Homoallylamines as formaldehyde-responsive triggers | HCAR2, MTHFD2, AHCY | ALDH1A1 675/4885GFER 319/4885DYRK1A 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.