Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060421 | 0.81 | HTR2A (0.47) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL7562805 | 0.80 | ALDH1A1 (0.47) | APLNRESR1CYP19A1ESR2HTR2A | |
| SCHEMBL3527192 | 0.79 | APLNR (0.46) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL30486651 | 0.79 | APLNR (0.46) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL8420644 | 0.78 | APLNR (0.44) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL1492044 | 0.78 | APLNR (0.63) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL12516104 | 0.77 | APLNR (0.41) | APLNRESR1CYP19A1ESR2CA12 | |
| SCHEMBL3677716 | 0.76 | KDM1A (0.44) | APLNRESR1CYP19A1ESR2HTR2A | |
| SCHEMBL473882 | 0.76 | SLC6A4 (0.46) | APLNRHTR2ACA12CA1CA2 | |
| SCHEMBL29976707 | 0.76 | SLC6A4 (0.46) | APLNRHTR2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307337-B1 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | UNIV CALIFORNIA (US) | 2016-01-13 | — | — | EP | disclosed |
| US-8674101-B2 | Nucleophilic fluorination of aromatic compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | disclosed |
| US-8674101-B2 | Nucleophilic fluorination of aromatic compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | disclosed |
| US-20110178302-A1 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| EP-2307337-A2 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | The Regents Of The University Of California (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010008522-A2 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178302-A1 | NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS | SLC18A2, AFF4, SLC6A19 | APLNR 3413/4885ESR1 1113/4885CYP19A1 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.