Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480434 | 0.79 | AURKA (0.47) | NR1H4MLKL | |
| SCHEMBL7069637 | 0.77 | TPSAB1 (0.44) | — | |
| SCHEMBL7075022 | 0.75 | TPSAB1 (0.44) | — | |
| SCHEMBL7072630 | 0.72 | TPSAB1 (0.44) | — | |
| SCHEMBL7075803 | 0.72 | TPSAB1 (0.46) | — | |
| SCHEMBL7072043 | 0.72 | TPSAB1 (0.42) | — | |
| SCHEMBL7482199 | 0.71 | PIN1 (0.38) | — | |
| SCHEMBL7067767 | 0.71 | NR1H4 (0.42) | NR1H4GLP1R | |
| SCHEMBL7071633 | 0.71 | TPSAB1 (0.48) | — | |
| SCHEMBL7405580 | 0.71 | TPSAB1 (0.40) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |