Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072186 | 0.83 | TPSAB1 (0.43) | NR1H4NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7490827 | 0.82 | ACSS2 (0.42) | AURKAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7489855 | 0.82 | PIN1 (0.46) | AURKAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7069754 | 0.82 | NPC1 (0.49) | KMT2AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7485173 | 0.82 | PIN1 (0.46) | KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7485673 | 0.82 | L3MBTL1 (0.44) | AURKAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7485199 | 0.82 | PIN1 (0.46) | KMT2AKDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7478353 | 0.81 | PIN1 (0.45) | AURKAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7397634 | 0.81 | L3MBTL1 (0.41) | KMT2AHPGDNPC1L3MBTL1 | |
| SCHEMBL7562865 | 0.79 | PDE4A (0.44) | NR1H4MLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |