Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042675 | 0.83 | REN (0.50) | RENSLC6A3 | |
| SCHEMBL6041854 | 0.81 | REN (0.47) | REN | |
| SCHEMBL27522709 | 0.80 | REN (0.50) | REN | |
| SCHEMBL7580189 | 0.79 | REN (0.50) | REN | |
| SCHEMBL6046424 | 0.78 | REN (0.49) | RENMCHR1 | |
| SCHEMBL6042395 | 0.75 | REN (0.80) | REN | |
| SCHEMBL6042921 | 0.74 | DRD2 (0.53) | RENMCHR1 | |
| SCHEMBL6042506 | 0.73 | CCR5 (0.50) | REN | |
| SCHEMBL6041685 | 0.73 | REN (0.46) | REN | |
| SCHEMBL6041307 | 0.72 | REN (0.52) | RENSLC6A2HTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |