Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 13/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046424 | 0.89 | REN (0.49) | RENKMT2ASIGMAR1 | |
| SCHEMBL6041685 | 0.86 | REN (0.46) | RENKMT2A | |
| SCHEMBL6042921 | 0.85 | DRD2 (0.53) | RENKMT2ASIGMAR1ACHE | |
| SCHEMBL6042506 | 0.84 | CCR5 (0.50) | RENKMT2ASIGMAR1 | |
| SCHEMBL6042947 | 0.82 | SIGMAR1 (0.49) | RENKMT2ASIGMAR1ACHE | |
| SCHEMBL7562935 | 0.79 | REN (0.47) | REN | |
| SCHEMBL6042675 | 0.76 | REN (0.50) | REN | |
| SCHEMBL6042868 | 0.76 | REN (0.44) | REN | |
| SCHEMBL27522709 | 0.75 | REN (0.50) | REN | |
| SCHEMBL6041307 | 0.74 | REN (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |