Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579935 | 0.99 | ALOX15 (0.60) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL28164487 | 0.94 | SMN1; SMN2 (0.53) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL27218058 | 0.88 | ALOX15 (0.56) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL19245015 | 0.87 | ALOX15 (0.75) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL19245014 | 0.86 | ALOX15 (0.77) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL16579940 | 0.85 | ALOX15 (0.55) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL6556860 | 0.85 | HCAR3 (0.63) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL19245016 | 0.85 | ALOX15 (0.71) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL24100991 | 0.84 | ALOX15 (0.56) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA | |
| SCHEMBL3742643 | 0.84 | ALOX15 (0.53) | ALOX15SMN1; SMN2HDAC8ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151534-A1 | Antithrombotic compounds | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151534-A1 | Antithrombotic compounds | SERPINC1, PF4, F2 | ALOX15 169/4885SMN1; SMN2 1107/4885HDAC8 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.