SCHEMBL7563335

SCHEMBL7563335

CC1(C)C(=O)CC(=O)N1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
LOX P28300 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
CYP3A4 P08684 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
DRD3 P35462 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MMP13 P45452 1/20 0.40
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11812858 0.70 PGR (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL1461676 0.69 AR (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19GAA
SCHEMBL8475478 0.68 IDH1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL8475475 0.68 IDH1 (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL22055779 0.67 CTSG (0.45) CYP1A2CYP2C9CYP2C19CYP3A4GAA
SCHEMBL3076873 0.66 MMP13 (0.41) ALDH1A1CYP1A2CYP2C9CYP2C19MEN1
SCHEMBL22054800 0.66 MMP13 (0.41) ALDH1A1CYP1A2CYP2C9CYP2C19LOX
SCHEMBL19923441 0.65 GRM4 (0.57) ALDH1A1GAA
SCHEMBL6224475 0.65 MMP13 (0.40) ALDH1A1CYP1A2CYP2C9CYP2C19GAA
SCHEMBL30393814 0.65 GRK5 (0.46) ALDH1A1MEN1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US disclosed
EP-0921433-B1 Thermographic recording elements FUJI PHOTO FILM CO LTD (JP) 2002-08-28 EP disclosed
US-6423486-B2 IMAGE FORMING LAYER IS MIXTURE OF ORGANIC SILVER SALT, REDUCING AGENT AND NUCLEATION AGENT FUJI PHOTO FILM CO., LTD. (JP) 2002-07-23 US disclosed
US-20010038984-A1 Thermographic recording elements FUJI PHOTO FILM CO., LTD. 2001-11-08 US disclosed
US-6232059-B1 ORGANIC SILVER SALT, A REDUCING AGENT, AND A SPECIFIC NUCLEATING AGENT; HIGH DMAX, HIGH SENSITIVITY, SATISFACTORY CONTRAST, LOW FOG, AND MINIMAL DEPENDENCY OF PHOTOGRAPHIC PROPERTIES ON DEVELOPING TEMPERATURE FUJI PHOTO FILM CO., LTD. (JP) 2001-05-15 US disclosed
EP-0921433-A1 Thermographic recording elements FUJI PHOTO FILM CO., LTD. (JP) 1999-06-09 EP disclosed