Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671956 | 0.90 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7674904 | 0.86 | MAPT (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7676892 | 0.86 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7677241 | 0.84 | NOD2 (0.47) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7674975 | 0.83 | NPC1 (0.44) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7677154 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4666381 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7676036 | 0.74 | MEN1 (0.51) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4560573 | 0.74 | ALDH1A1 (0.51) | ALDH1A1NPC1MAPTLMNAHTT | |
| SCHEMBL7668980 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244653-A1 | NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001046176-A2 | NON PEPTIDE TACHYKININ RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |