Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563356 | 0.86 | KMT2A (0.51) | MAPTGAAMGAMSIMGAM2 | |
| SCHEMBL7671956 | 0.82 | ALDH1A1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL7676892 | 0.78 | ALDH1A1 (0.43) | MAPTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL7677327 | 0.77 | MAPT (0.45) | MAPTSMN1; SMN2METSMOGAA | |
| SCHEMBL7674975 | 0.76 | NPC1 (0.44) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7677154 | 0.75 | ALDH1A1 (0.44) | MAPTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL4250091 | 0.72 | ELANE (0.41) | MAPTSMN1; SMN2METSMOGAA | |
| SCHEMBL7677241 | 0.72 | NOD2 (0.47) | MAPTSMN1; SMN2GAAMGAMSI | |
| SCHEMBL27946627 | 0.71 | SRC (0.53) | MAPTSMN1; SMN2GAAMGAMSI | |
| SCHEMBL7650108 | 0.70 | MEN1 (0.49) | MAPTSMN1; SMN2METSMOGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |