SCHEMBL7563469

SCHEMBL7563469

CCC1(C(=O)O)CCOC1=O

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8197883 0.85 LMNA (0.32) LMNACYP2C9
SCHEMBL8593083 0.85 ALDH1A1 (0.34) LMNACYP2C9
SCHEMBL30275680 0.79 ATM (0.43)
SCHEMBL8459306 0.78 CYP2C9 (0.32) LMNACYP2C9
SCHEMBL3389445 0.72 ALDH1A1 (0.36) LMNACYP2C9
SCHEMBL7618116 0.72 NAAA (0.39)
SCHEMBL10701530 0.69
SCHEMBL21703600 0.69 ATM (0.41)
SCHEMBL576533 0.69 LMNA (0.34) LMNACYP2C9
SCHEMBL20955869 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222184-A2 PREPARATION AND USE OF GAMMA-BUTYROLACTONES AS CROSS-LINKING AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-07-17 EP disclosed
WO-2000078743-A2 PREPARATION AND USE OF GAMMA-BUTYROLACTONES AS CROSS-LINKING AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-28 WO disclosed