Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593083 | 0.81 | ALDH1A1 (0.34) | CYP2C9CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL7563469 | 0.78 | LMNA (0.33) | CYP2C9LMNA | |
| SCHEMBL8197883 | 0.75 | LMNA (0.32) | CYP2C9LMNA | |
| SCHEMBL30275680 | 0.72 | ATM (0.43) | TSHR | |
| SCHEMBL3389445 | 0.69 | ALDH1A1 (0.36) | CYP2C9CYP3A4ALOX15TSHRCYP2C19 | |
| SCHEMBL10701530 | 0.67 | — | — | |
| SCHEMBL6960808 | 0.67 | LMNA (0.31) | CYP2C9LMNA | |
| SCHEMBL576533 | 0.66 | LMNA (0.34) | CYP2C9LMNA | |
| SCHEMBL8583847 | 0.66 | PRKCA (0.39) | CYP2C9LMNA | |
| SCHEMBL6961163 | 0.65 | PRKCA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |