Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 6/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560533 | 0.84 | CASR (0.65) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7560544 | 0.84 | CASR (0.65) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7560541 | 0.84 | CASR (0.65) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8169408 | 0.81 | KEAP1 (0.45) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8167993 | 0.81 | ALDH1A1 (0.47) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6220841 | 0.78 | CASR (0.63) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8172490 | 0.78 | CASR (0.46) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7563830 | 0.78 | CASR (0.46) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8172146 | 0.77 | CASR (0.49) | CASRSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8166977 | 0.75 | KCNH2 (0.49) | CASRSLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072760-A2 | PCRA HELICASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-19 | — | — | WO | claimed |