Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632240 | 0.92 | ALDH1A1 (0.46) | TSHRALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29662115 | 0.90 | TAS1R3 (0.35) | TSHRALDH1A1ACACBMEN1CYP2D6 | |
| Methacrylic Acid SCHEMBL28158162 | 0.89 | ALDH1A1 (0.44) | TSHRALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6384996 | 0.85 | ALDH1A1 (0.42) | TSHRALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14136428 | 0.82 | L3MBTL1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6385004 | 0.81 | SMN1; SMN2 (0.44) | TSHRALDH1A1KDM4E | |
| SCHEMBL8394453 | 0.80 | SLC1A3 (0.44) | TSHRALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8733208 | 0.79 | TSHR (0.41) | TSHRCYP2C9 | |
| SCHEMBL9404696 | 0.78 | SLC6A2 (0.32) | TSHR | |
| SCHEMBL3007166 | 0.78 | ALDH1A1 (0.46) | TSHRALDH1A1PPARAPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940694-B1 | Photochromic curable composition | TOKUYAMA CORP (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6194511-B1 | COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0940694-A1 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 1999-09-08 | — | — | EP | disclosed |