Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149086 | 0.86 | NPC1 (0.39) | CISD2CA12CA1CA2CA9 | |
| SCHEMBL3842336 | 0.84 | L3MBTL1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6351061 | 0.84 | CSNK2A1 (0.41) | CISD2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16426100 | 0.83 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL7594883 | 0.83 | CA12 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12301378 | 0.82 | KMT2A (0.44) | CISD2NPC1RAB9AHTTMEN1 | |
| SCHEMBL1578885 | 0.81 | GABRA1 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL22366366 | 0.81 | FLT1 (0.43) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL14329237 | 0.81 | GABRG2 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13171452 | 0.81 | CA12 (0.39) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962779-B2 | Method of forming polyaryl polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | SCHERING AG | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | TNNI3, NPR1, LPXN | CISD2 2363/4885CA12 2329/4885CA1 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.