SCHEMBL7564079

SCHEMBL7564079

C[SiH](c1ccccc1)[Zr](Cl)(Cl)(C1C=Cc2c(-c3ccccn3)cccc21)C1C=Cc2c(-c3ccccn3)cccc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7569794 0.88 ADRA1A (0.32) ADRA1A
SCHEMBL7565970 0.88 ADRA1A (0.33) ADRA1A
SCHEMBL7571161 0.82 MAOA (0.31)
SCHEMBL7564355 0.79 ADRA1A (0.31) ADRA1A
Hydrochloric Acid SCHEMBL7565976 0.76 ADRA1A (0.34) ADRA1A
Hydrochloric Acid SCHEMBL7564081 0.74 ADRA1A (0.32) ADRA1A
Hydrochloric Acid SCHEMBL7569797 0.74 ADRA1A (0.33) ADRA1A
SCHEMBL5952333 0.74 CYP1A2 (0.31)
SCHEMBL216045 0.72 SIGMAR1 (0.31)
SCHEMBL7571442 0.72 MAOA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US claimed
EP-0743317-B1 Metallocenes comprising a heterocycle and catalysts containing them BASELL POLYOLEFINE GMBH (DE) 2002-08-28 EP disclosed
US-5840947-A Organometallic compound TARGOR GMBH (DE) 1998-11-24 US disclosed
EP-0743317-A2 Metallocenes comprising a heterocycle and catalysts containing them HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-20 EP disclosed