Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | FADS1 | O60427 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TACR3 | P29371 | 3/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565766 | 0.87 | AOX1 (0.46) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7566344 | 0.87 | HDAC1 (0.48) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7565639 | 0.86 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7564414 | 0.86 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7565049 | 0.86 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7568076 | 0.86 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7564805 | 0.84 | KDM4E (0.49) | AOX1TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7570917 | 0.84 | AOX1 (0.44) | AOX1HDAC1HDAC6RAD52TACR3 | |
| SCHEMBL7566419 | 0.84 | AOX1 (0.44) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7567278 | 0.83 | AOX1 (0.38) | AOX1TAS1R3TAS1R1TAS1R2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |