Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566344 | 0.89 | HDAC1 (0.48) | AOX1HDAC1HDAC6PARP1MEN1 | |
| SCHEMBL7564414 | 0.88 | AOX1 (0.45) | AOX1HDAC1HDAC6PARP1MEN1 | |
| SCHEMBL7568076 | 0.88 | AOX1 (0.45) | AOX1HDAC1HDAC6MAPTKDM4E | |
| SCHEMBL7565049 | 0.88 | AOX1 (0.45) | AOX1HDAC1HDAC6PARP1MAPT | |
| SCHEMBL7565639 | 0.88 | AOX1 (0.45) | AOX1HDAC1HDAC6LMNAHTT | |
| SCHEMBL7564186 | 0.87 | AOX1 (0.44) | AOX1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7564805 | 0.86 | KDM4E (0.49) | AOX1PARP1MEN1KMT2AMAPT | |
| SCHEMBL7570917 | 0.86 | AOX1 (0.44) | AOX1HDAC1HDAC6PARP1ALDH1A1 | |
| SCHEMBL7566419 | 0.86 | AOX1 (0.44) | AOX1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL7566548 | 0.85 | MAPT (0.45) | MEN1KMT2AMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |