Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564033 | 0.92 | HDAC1 (0.40) | AOX1HDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL7565766 | 0.88 | AOX1 (0.46) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7566344 | 0.88 | HDAC1 (0.48) | AOX1HDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL7565639 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6GAATAS1R3 | |
| SCHEMBL7564414 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6ALDH1A1GAA | |
| SCHEMBL7568076 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7564186 | 0.86 | AOX1 (0.44) | AOX1HDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7564805 | 0.85 | KDM4E (0.49) | AOX1ALDH1A1GAAKDM4ETAS1R3 | |
| SCHEMBL7566419 | 0.85 | AOX1 (0.44) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7570917 | 0.85 | AOX1 (0.44) | AOX1HDAC1HDAC6ALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |