Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572103 | 0.92 | AOX1 (0.39) | AOX1HDAC1HDAC6GAALMNA | |
| SCHEMBL7565766 | 0.88 | AOX1 (0.46) | AOX1HDAC1HDAC6LMNATAS1R3 | |
| SCHEMBL7566344 | 0.88 | HDAC1 (0.48) | AOX1HDAC1HDAC6GAATAS1R3 | |
| SCHEMBL7568076 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6TAS1R3TAS1R1 | |
| SCHEMBL7564414 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6GAALMNA | |
| SCHEMBL7565049 | 0.87 | AOX1 (0.45) | AOX1HDAC1HDAC6GAALMNA | |
| SCHEMBL7564186 | 0.86 | AOX1 (0.44) | AOX1HDAC1HDAC6LMNATAS1R3 | |
| SCHEMBL7570917 | 0.85 | AOX1 (0.44) | AOX1HDAC1HDAC6TACR3SMN1; SMN2 | |
| SCHEMBL7564805 | 0.85 | KDM4E (0.49) | AOX1TSHRGAATAS1R3TAS1R1 | |
| SCHEMBL7566419 | 0.85 | AOX1 (0.44) | AOX1HDAC1HDAC6TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |