SCHEMBL7564326

SCHEMBL7564326

O=COc1cccc2nc3ccccc3nc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 11/20 0.59
MAPT P10636 5/20 0.46
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 2/20 0.45
THRB P10828 2/20 0.45
BLM P54132 2/20 0.45
MEN1 O00255 1/20 0.45
CASP6 P55212 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPC1 O15118 2/20 0.45
LMNA P02545 1/20 0.45
G6PD P11413 1/20 0.45
PKM P14618 1/20 0.45
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14648930 0.80 ALDH1A1 (0.61) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL2291623 0.78 NQO2 (0.70) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL2629413 0.75 NQO2 (0.37) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL6007444 0.75 NQO2 (0.50) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL182949 0.75 NQO2 (0.66) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL1513023 0.75 NQO2 (1.00) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL4775529 0.74 MAPT (0.44) MAPTRAB9AALDH1A1KMT2AGAA
SCHEMBL6213177 0.74 NQO2 (0.59) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL14648915 0.74 ACHE (0.51) NQO2MAPTRAB9AALDH1A1KMT2A
SCHEMBL28375189 0.74 NQO2 (0.54) NQO2MAPTRAB9AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510419-A Free radical material containing phenazine carboxylic acid inner salt, preparation method and application thereof 华南理工大学 2024-02-06 CN claimed
EP-0934278-B1 BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS XENOVA LTD (GB) 2002-09-04 EP claimed
US-6114332-A BACTERICIDES XENOVA LIMITED (GB) 2000-09-05 US claimed
EP-0934278-A1 BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS XENOVA LIMITED (GB) 1999-08-11 EP claimed
WO-1998017650-A1 BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS XENOVA LIMITED (GB) 1998-04-30 WO claimed
CN-119931087-A Zirconium metal organic framework material based on phenazine and preparation method and application thereof 西安石油大学 2025-05-06 CN disclosed
CN-117510419-A Free radical material containing phenazine carboxylic acid inner salt, preparation method and application thereof 华南理工大学 2024-02-06 CN disclosed
CN-117510419-A Free radical material containing phenazine carboxylic acid inner salt, preparation method and application thereof 华南理工大学 2024-02-06 CN disclosed
CN-117510419-A Free radical material containing phenazine carboxylic acid inner salt, preparation method and application thereof 华南理工大学 2024-02-06 CN disclosed
US-11820973-B2 Methods and system for interfering with viability of bacteria and related compounds and compositions CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-11-21 US disclosed
CN-114891670-B Siamese bacillus ZJh with broad-spectrum antibacterial property and application thereof 岭南师范学院 2023-09-19 CN disclosed
CN-114891670-A Bacillus siamensis ZJh with broad-spectrum antibacterial activity and application thereof 岭南师范学院 2022-08-12 CN disclosed
US-5679560-A ENZYME REQUIRED IN BIOSYNTHETIC PATHWAY OF PYRROLNITRIN; PROTECTION OF PLANTS AGAINST PHYTOPATHOGENS NOVARTIS FINANCE CORPORATION (US) 1997-10-21 US disclosed
US-5662898-A Genes for the synthesis of antipathogenic substances CIBA-GEIGY CORPORATION (US) 1997-09-02 US disclosed
US-5643774-A DNA MOLECULES WITH POLYPEPTIDES FORMED BY BIOSYNTHESIS CIBA-GEIGY CORPORATION (US) 1997-07-01 US disclosed
US-5639949-A DNA MOLECULE ENCODING ONE OR MORE POLYPEPTIDES REQUIRED FOR THE BIOSYNTHESIS OF PYRROLNITRIN CIBA-GEIGY CORPORATION (US) 1997-06-17 US disclosed
EP-0759078-A1 GENES FOR THE SYNTHESIS OF ANTIPATHOGENIC SUBSTANCES Novartis AG (CH) 1997-02-26 EP disclosed
WO-1995033818-A2 GENES FOR THE SYNTHESIS OF ANTIPATHOGENIC SUBSTANCES CIBA-GEIGY AG (CH) 1995-12-14 WO disclosed
US-4593097-A ANTIBACTERIAL AND ANTITUMOR ACTIVITY KYOWA HAKKO KOGYO CO., LTD. (JP) 1986-06-03 US disclosed
EP-0172744-A2 Phenazinecarboxamide compounds DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) 1986-02-26 EP disclosed