Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6041923 | 0.84 | SLC6A1 (0.43) | SLC6A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7077994 | 0.82 | SLC6A1 (0.41) | SLC6A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7084618 | 0.78 | SLC6A1 (0.38) | SLC6A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7593801 | 0.75 | REN (0.41) | KIF11 | |
| SCHEMBL6043281 | 0.73 | SLC6A1 (0.39) | SLC6A1SLC18A3SLC6A11HTTCYP2C19 | |
| SCHEMBL6958316 | 0.72 | SLC6A1 (0.38) | SLC6A1CHRM3SLC18A3SLC6A11HTT | |
| SCHEMBL6042383 | 0.70 | SLC6A1 (0.39) | SLC6A1CHRM2CHRM1CHRM3SLC18A3 | |
| SCHEMBL6041453 | 0.68 | REN (0.46) | — | |
| SCHEMBL6951927 | 0.67 | TACR1 (0.36) | SLC6A1SLC18A3SLC6A11HTTMEN1 | |
| SCHEMBL9142722 | 0.66 | KIF11 (0.52) | CYP2C19KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |