Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554119 | 0.84 | DGAT1 (0.43) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL2582578 | 0.84 | DGAT1 (0.43) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL3622009 | 0.84 | DGAT1 (0.43) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL27492837 | 0.83 | BLM (0.44) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL27492836 | 0.83 | BLM (0.44) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL9042229 | 0.76 | LMNA (0.46) | MIFESR1ESR2CYP3A4LMNA | |
| SCHEMBL192800 | 0.76 | CYP19A1 (0.45) | MIFCYP3A4HSD17B10ALDH1A1MAPK1 | |
| SCHEMBL4689225 | 0.76 | LMNA (0.46) | MIFESR1ESR2CYP3A4LMNA | |
| SCHEMBL15105740 | 0.73 | ESR1 (0.46) | ELANEMIFESR1ESR2CYP3A4 | |
| SCHEMBL4023625 | 0.72 | KIF11 (0.43) | ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068428-A1 | METHOD OF PREPARING CEPHALOSPORINS USING 4-HYDROXYPHENYLGLYCINE DERIVATIVES | HANMI PHARM. CO., LTD. (KR) | 2002-09-06 | — | — | WO | disclosed |
| US-20020120136-A1 | Method of preparing cephalosporins using 4-hydroxyphenylglycine derivatives | HANMI PHARM. CO., LTD. (KR) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120136-A1 | Method of preparing cephalosporins using 4-hydroxyphenylglycine derivatives | GYPA, PEPD, HPD | ELANE 3849/4885MIF 4476/4885ESR1 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.