SCHEMBL153131

SCHEMBL153131

Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 1.00
CA2 P00918 12/20 1.00
CA9 Q16790 5/20 1.00
HTT P42858 1/20 1.00
CA12 O43570 4/20 0.76
KMT2A Q03164 2/20 0.70
KEAP1 Q14145 1/20 0.70
USP2 O75604 1/20 0.65
TSHR P16473 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
CA5A P35218 1/20 0.65
CA7 P43166 1/20 0.65
CA13 Q8N1Q1 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
AGO2 Q9UKV8 1/20 0.65
CA14 Q9ULX7 1/20 0.65
CA5B Q9Y2D0 1/20 0.65
PRMT1 Q99873 1/20 0.65
MEN1 O00255 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540915 0.92 CA1 (0.85) CA1CA2CA9HTTCA12
SCHEMBL11793140 0.92 CA1 (0.85) CA1CA2CA9HTTCA12
SCHEMBL19603195 0.86 CA1 (0.76) CA1CA2CA9HTTCA12
SCHEMBL27466837 0.85 CA1 (1.00) CA1CA2CA9HTTCA12
SCHEMBL11683906 0.83 CA1 (0.71) CA1CA2CA9HTTCA12
SCHEMBL2240008 0.83 CA1 (0.71) CA1CA2CA9HTTCA12
SCHEMBL1417537 0.83 CA1 (0.71) CA1CA2CA9HTTCA12
SCHEMBL7565259 0.83 CA1 (0.73) CA1CA2CA9HTTCA12
SCHEMBL4573594 0.83 CA1 (0.74) CA1CA2CA9HTTKMT2A
SCHEMBL3086764 0.83 CA1 (0.74) CA1CA2CA9HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 765 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10449247-B2 Compositions and methods for enhancing immune response AVIVAGEN INC. (CA) 2019-10-22 US claimed
EP-2953624-B1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LUODA PHARMA LTD (IE) 2019-08-21 EP claimed
US-9402697-B2 Modification of ceramic surfaces RESEARCH TRIANGLE INSTITUTE (US) 2016-08-02 US claimed
US-20160000748-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Limited (IE) 2016-01-07 US claimed
US-20150366797-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Limited (IE) 2015-12-24 US claimed
EP-2953623-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP claimed
EP-2953624-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS Luoda Pharma Pty Ltd (AU) 2015-12-16 EP claimed
US-8993117-B2 Devices with multiple surface functionality THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-03-31 US claimed
US-20150064654-A1 MODIFICATION OF CERAMIC SURFACES RES TRIANGLE INST (US) 2015-03-05 US claimed
WO-2014121342-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS LUODA PHARMA PTY LIMITED (AU) 2014-08-14 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
US-6172069-B1 CONTROLLING TIME OF ADMINISTERING G. D. SEARLE & COMPANY 2001-01-09 US claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061537-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0981273-A1 ADHESIVE, ANTIMICROBIAL AND/OR REPARATIVE DENTIN STIMULATING DENTAL COMPOSITIONS AND METHODS FOR FORMING AND USING SUCH COMPOSITIONS Ultradent Products, Inc. (US) 2000-03-01 EP claimed
WO-1998036639-A1 ADHESIVE, ANTIMICROBIAL AND/OR REPARATIVE DENTIN STIMULATING DENTAL COMPOSITIONS AND METHODS FOR FORMING AND USING SUCH COMPOSITIONS ULTRADENT PRODUCTS, INC. (US) 1998-08-27 WO claimed
EP-0741570-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1996-11-13 EP claimed
WO-1995020387-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1995-08-03 WO claimed
WO-1992014456-A1 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY SHAPIRO HOWARD K (US) 1992-09-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000748-A1 METHODS OF TREATING TOPICAL MICROBIAL INFECTIONS TSLP, CCL11, IL17A CA1 2912/4885CA2 204/4885CA9 792/4885
US-20150366797-A1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LCT, TSLP, MLEC CA1 1919/4885CA2 311/4885CA9 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.