Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570480 | 0.92 | SLC6A12 (0.48) | HTR7CCR3HTR4 | |
| SCHEMBL6219344 | 0.91 | MTTP (0.46) | HTR7CCR3DRD4ADRA1AADRA1D | |
| SCHEMBL7242152 | 0.91 | HTR7 (0.49) | HTR7CCR3DRD4ADRA1AADRA1D | |
| SCHEMBL7570492 | 0.90 | MTTP (0.47) | HTR7CCR3DRD4ADRA1AMTTP | |
| SCHEMBL7571721 | 0.90 | POLB (0.47) | HTR7CCR3DRD4MAOBPOLB | |
| SCHEMBL7569221 | 0.88 | KCNA3 (0.42) | HTR7CCR3DRD4ADRA1AADRA1D | |
| Bicarbonate SCHEMBL7565338 | 0.86 | HTR7 (0.43) | HTR7CCR3DRD4ADRA1AADRA1D | |
| Bicarbonate SCHEMBL7569224 | 0.85 | HTR7 (0.43) | HTR7CCR3DRD4ADRA1AADRA1D | |
| SCHEMBL6219359 | 0.85 | MTTP (0.46) | HTR7CCR3DRD4ADRA1AMTTP | |
| SCHEMBL6216661 | 0.84 | MTTP (0.56) | HTR7CCR3DRD4ADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202969-A2 | BIPHENYL DERIVATIVES, PRODUCTION THEREOF AND USE AS MEDICINES | Boehringer Ingelheim Pharma KG (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005762-A2 | BIPHENYL DERIVATIVES, PRODUCTION THEREOF AND USE AS MTP INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-25 | — | — | WO | disclosed |