SCHEMBL2891962

SCHEMBL2891962

O=C(O)CCCOc1ccc(CO)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 6/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ PPARA Q07869 3/20 0.54
▸ FFAR4 Q5NUL3 6/20 0.54
▸ PPARG P37231 1/20 0.52
▸ LTA4H P09960 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710391 0.95 PPARA (0.61) FFAR1L3MBTL1LMNAPPARALTA4H
SCHEMBL854425 0.91 L3MBTL1 (0.65) FFAR1L3MBTL1LMNAPPARAFFAR4
SCHEMBL31448501 0.88 PPARA (0.65) FFAR1L3MBTL1LMNAPPARAFFAR4
SCHEMBL10728695 0.85 PLA2G4B (0.59) FFAR1L3MBTL1LMNAPPARAPPARG
SCHEMBL8449777 0.85 LTA4H (0.50) FFAR1L3MBTL1LMNALTA4H
SCHEMBL7565477 0.84 FFAR1 (0.67) FFAR1L3MBTL1LMNAPPARAFFAR4
SCHEMBL10207287 0.84 LMNA (0.63) FFAR1L3MBTL1LMNAPPARAFFAR4
SCHEMBL31448470 0.82 PPARA (0.73) FFAR1L3MBTL1LMNAPPARA
SCHEMBL16902877 0.82 HRH3 (0.59) L3MBTL1LMNALTA4H
SCHEMBL8545935 0.82 HRH3 (0.59) FFAR1L3MBTL1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227813-B1 REVERSE-TURN MIMETICS AS alpha 4ß INTEGRIN INHIBITORS MYRIAD GENETICS INC (US) 2007-08-22 — — EP claimed
CN-108770357-B Polymer conjugate vaccines 芝加哥大学 2022-10-28 — — CN disclosed
US-20150057283-A1 REVERSE-TURN MIMETICS AND METHOD RELATING THERETO CHOONGWAE PHARMA CORPORATION (KR) 2015-02-26 — — US disclosed
US-8729262-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2014-05-20 — — US disclosed
US-8318738-B2 Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2012-11-27 — — US disclosed
US-20100216992-A1 MIMETIC COMPOSITIONS AND THE PRODUCTION THEREOF UNIVERSITY OF SOUTH FLORIDA (US) 2010-08-26 — — US disclosed
US-7642344-B2 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES, INC. (US) 2010-01-05 — — US disclosed
US-7598253-B2 Reverse-turn mimetics and methods relating thereto MYRIAD GENETICS, INC. (US) 2009-10-06 — — US disclosed
EP-0962537-B1 Methods for analyzing nucleic acid molecules utilizing sizing techniques OPERON BIOTECHNOLOGIES INC (US) 2009-06-17 — — EP disclosed
EP-0992511-B1 Methods and compositions for determining the sequence of nucleic acid molecules OPERON BIOTECHNOLOGIES INC (US) 2009-03-11 — — EP disclosed
EP-0850320-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL DARWIN MOLECULAR CORPORATION (US) 1998-07-01 — — EP disclosed
US-5773001-A ANTIGROWTH AGENTS AMERICAN CYANAMID COMPANY (US) 1998-06-30 — — US disclosed
US-5767285-A USEFUL FOR CONSTRUCTING DRUG CONJUGATES; ANTIBIOTIC ANTITUMOR AGENTS AMERICAN CYANAMID COMPANY (US) 1998-06-16 — — US disclosed
EP-0840804-A1 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES DARWIN MOLECULAR CORPORATION (US) 1998-05-13 — — EP disclosed
US-5739116-A DISULFIDE DERIVATIVE OF CALICHEAMICIN FAMILY; ANTITUMOR ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1998-04-14 — — US disclosed
WO-1997027331-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES — 1997-10-09 — — WO disclosed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 — — WO disclosed
WO-1997027327-A2 METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL RAPIGENE, INC. (US) 1997-07-31 — — WO disclosed
WO-1997027325-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES RAPIGENE, INC. (US) 1997-07-31 — — WO disclosed
EP-0689845-A2 Conjugates of methyltrithio antitumor agents and intermediates for their synthesis AMERICAN CYANAMID COMPANY (US) 1996-01-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216992-A1 MIMETIC COMPOSITIONS AND THE PRODUCTION THEREOF BID, BCL2L1, BCL2A1 FFAR1 4437/4885L3MBTL1 1107/4885LMNA 2348/4885
US-20150057283-A1 REVERSE-TURN MIMETICS AND METHOD RELATING THERETO WNT1, APC, WNT3 FFAR1 3408/4885L3MBTL1 1783/4885LMNA 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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