SCHEMBL7565512

SCHEMBL7565512

CCOC(=O)Nc1ccc(NC(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.70
NPC1 O15118 3/20 0.70
HPGD P15428 2/20 0.70
CRHBP P24387 1/20 0.70
CRHR2 Q13324 1/20 0.70
SMN1; SMN2 Q16637 4/20 0.59
LMNA P02545 2/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPT P10636 2/20 0.58
MAPK1 P28482 1/20 0.58
ALDH1A1 P00352 3/20 0.58
TSHR P16473 2/20 0.58
KDM4E B2RXH2 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
RECQL P46063 1/20 0.58
NPSR1 Q6W5P4 1/20 0.57
CYP2C9 P11712 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP2D6 P10635 2/20 0.56
CYP1A2 P05177 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565510 0.94 RAB9A (0.71) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL10205641 0.89 RAB9A (0.61) RAB9ANPC1HPGDCRHBPCRHR2
Ethyl Phenylcarbamate SCHEMBL11593824 0.88 RAB9A (0.75) RAB9ANPC1HPGDCRHBPCRHR2
Ethyl Phenylcarbamate SCHEMBL264865 0.88 RAB9A (0.75) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL11790359 0.88 RAB9A (0.65) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL1719720 0.88 SMN1; SMN2 (0.71) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL9146676 0.88 LMNA (0.68) RAB9ANPC1HPGDCRHBPCRHR2
Benzene SCHEMBL11603590 0.87 RAB9A (0.69) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL7562461 0.87 SMN1; SMN2 (0.69) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL10668920 0.87 RAB9A (0.64) RAB9ANPC1HPGDCRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed