Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CRHBP | P24387 | 1/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565510 | 0.94 | RAB9A (0.71) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| Urethane SCHEMBL10734196 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL8737482 | 0.91 | NPC1 (0.79) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL11790359 | 0.88 | RAB9A (0.65) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL7565512 | 0.88 | RAB9A (0.70) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL9146676 | 0.88 | LMNA (0.68) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL11326733 | 0.87 | RAB9A (0.60) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL10192026 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL19390510 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 | |
| SCHEMBL352811 | 0.86 | RAB9A (0.63) | SMN1; SMN2ALDH1A1LMNARECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102498095-A | Indoline derivatives | TOKYO INST TECH | 2012-06-13 | — | — | CN | claimed |
| US-11697636-B2 | Substituted benzamides | HOFFMANN-LA ROCHE INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-11518766-B2 | Tricyclic compound, preparation method therefor and use thereof | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD. (CN) | 2022-12-06 | — | — | US | disclosed |
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |
| EP-3853305-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | ModernaTX, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3508473-B1 | METHOD FOR PRODUCING CARBAMIC ACID ESTER | AIST (JP) | 2021-05-26 | — | — | EP | disclosed |
| EP-3720833-A1 | PROPELLANT CHARGE | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk Onderzoek TNO (NL) | 2020-10-14 | — | — | EP | disclosed |
| US-10752579-B2 | Production method of carbamic acid ester | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2020-08-25 | — | — | US | disclosed |
| WO-2020061295-A1 | HIGH-PURITY PEG LIPIDS AND USES THEREOF | MODERNATX, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2018227012-A9 | POLYMER-LIPID MATERIALS FOR DELIVERY OF NUCLEIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-11-14 | — | — | WO | disclosed |
| US-4550150-A | COLORIMETRIC DETECTION | ALLIED CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |
| US-4375000-A | Process for the preparation of an aryl mono-, di-, and/or polyurethane | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-22 | — | — | US | disclosed |
| US-4294925-A | FERMENTATION, AEROBIC PROCESSES | HOFFMANN-LA ROCHE INC. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4263427-A | REACTING HYDROXYL WITH ISOCYANATE TO OBTAIN ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4186269-A | REACTING AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE IN PRESENCE OF CATALYST | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1980-01-29 | — | — | US | disclosed |
| US-4151154-A | COUPLERS, SURFACTANTS | UNION CARBIDE CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4136080-A | REINFORCED WITH A SILANE - TREATED ALUMINA HYDRATE | UNION CARBIDE CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |
| US-4105465-A | COATED WITH A SILANE CONTAINING HYDROLYZABLE GROUPS AND A POLYALKYLENE OXIDE GROUP | UNION CARBIDE CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518766-B2 | Tricyclic compound, preparation method therefor and use thereof | TFPI, TFPI2, F11 | SMN1; SMN2 3397/4885ALDH1A1 3573/4885LMNA 601/4885 |
| US-10752579-B2 | Production method of carbamic acid ester | CA2, CA7, CA4 | SMN1; SMN2 3068/4885ALDH1A1 3215/4885LMNA 3973/4885 |
| US-11697636-B2 | Substituted benzamides | TAAR1, TAAR5, NPY1R | SMN1; SMN2 1965/4885ALDH1A1 440/4885LMNA 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.