SCHEMBL7565659

SCHEMBL7565659

CCC(C)(NC(=O)c1cc(Cl)c(OC)c(Cl)c1)C(=O)CCl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 1/20 0.55
TAS1R3 Q7RTX0 3/20 0.46
TAS1R1 Q7RTX1 3/20 0.46
TAS1R2 Q8TE23 3/20 0.46
HPGD P15428 2/20 0.45
KMT2A Q03164 3/20 0.44
HTT P42858 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.41
PKM P14618 2/20 0.39
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
TPMT P51580 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565086 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EGAAHPGDKMT2A
Zoxamide SCHEMBL70113 0.85 LMNA (0.36) ALDH1A1KDM4EGAATAS1R3TAS1R1
Zoxamide SCHEMBL7170744 0.85 LMNA (0.36) ALDH1A1KDM4EGAATAS1R3TAS1R1
Zoxamide SCHEMBL170285 0.85 LMNA (0.36) ALDH1A1KDM4EGAATAS1R3TAS1R1
Zoxamide SCHEMBL17701171 0.84 LMNA (0.35) ALDH1A1KDM4EGAATAS1R3TAS1R1
SCHEMBL7572038 0.84 HSD17B13 (0.36) ALDH1A1KDM4EGAAHPGDKMT2A
SCHEMBL7527475 0.84 HSD11B1 (0.38) ALDH1A1KDM4EGAAHTTL3MBTL1
SCHEMBL8058941 0.83 ALDH1A1 (0.33) ALDH1A1KDM4EGAAHPGDKMT2A
SCHEMBL7530423 0.82 GRN (0.43) ALDH1A1GAARAB9AMAPTCYP2D6
SCHEMBL8059003 0.82 LMNA (0.33) ALDH1A1KDM4EGAAKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946093-B1 FUNGICIDAL COMPOSITIONS BASED ON (N-PHENYLACETYL-N-2,6-XYLYL)METHYL ALANINATE ISAGRO SPA (IT) 2002-08-28 EP claimed