Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NCS1 | P62166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.34 |
| ▸ | MICA | Q29983 | 2/20 | 0.34 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572103 | 0.87 | AOX1 (0.39) | AOX1TAS1R3TAS1R1PARP1HDAC1 | |
| SCHEMBL7566344 | 0.85 | HDAC1 (0.48) | AOX1TAS1R3TAS1R1PARP1HDAC1 | |
| SCHEMBL7565768 | 0.85 | AOX1 (0.44) | FGFR4HDAC11MAPKAPK2AOX1TAS1R3 | |
| SCHEMBL7566165 | 0.85 | TAS1R3 (0.39) | AOX1TAS1R3TAS1R1CTSSCTSK | |
| SCHEMBL7564033 | 0.85 | HDAC1 (0.40) | AOX1TAS1R3TAS1R1PARP1HDAC1 | |
| SCHEMBL7566453 | 0.84 | CTSS (0.47) | HDAC11TAS1R3TAS1R1CTSSCTSK | |
| SCHEMBL7566479 | 0.84 | AOX1 (0.42) | AOX1TAS1R3TAS1R1PARP1HDAC1 | |
| SCHEMBL7566419 | 0.83 | AOX1 (0.44) | AOX1TAS1R3TAS1R1HDAC1HDAC6 | |
| SCHEMBL7567197 | 0.83 | KDM4E (0.48) | TAS1R3TAS1R1PARP1ALDH1A1POLB | |
| SCHEMBL7565639 | 0.81 | AOX1 (0.45) | AOX1TAS1R3TAS1R1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |