Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028848 | 0.82 | MAPT (0.38) | GSK3BALDH1A1MAPT | |
| SCHEMBL28471872 | 0.79 | TP53 (0.42) | ALDH1A1MAPT | |
| SCHEMBL6317665 | 0.78 | KCNA5 (0.41) | GSK3BTNFADRA1DADRA1AADRA2B | |
| SCHEMBL28900487 | 0.78 | MEN1 (0.41) | ADRA1DMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28351722 | 0.75 | SRC (0.52) | GSK3BTNFGRM4GPR139MEN1 | |
| SCHEMBL28860721 | 0.74 | LOXL2 (0.40) | ADRA1DALDH1A1 | |
| SCHEMBL6163795 | 0.73 | ENPP2 (0.46) | GSK3BTNFADRA1DADRA1AADRA2B | |
| SCHEMBL8028851 | 0.73 | ALDH1A1 (0.48) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28224173 | 0.72 | MEN1 (0.47) | ADRA2BMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1043636 | 0.71 | PDCD1 (0.51) | GSK3BTNFGRM4GPR139CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | claimed |
| EP-0817615-B1 | PERORAL COMPOSITION FOR CONTROLLED RELEASE IN THE LOWER GASTROINTESTINAL TRACT | ORION YHTYMAE OY (FI) | 2002-08-07 | — | — | EP | disclosed |
| US-5962024-A | DRUG RELEASE CONTROLLING AGENT CONSISTS SUBSTANTIALLY OF A PH-SENSITIVE ENTERIC POLYMER. | ORION-YHTYMA OY (FI) | 1999-10-05 | — | — | US | disclosed |
| EP-0817615-A2 | PERORAL COMPOSITION FOR CONTROLLED RELEASE IN THE LOWER GASTROINTESTINAL TRACT | ORION-YHTYMÄ OY (FI) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996029058-A1 | PERORAL COMPOSITION FOR CONTROLLED RELEASE IN THE LOWER GASTROINTESTINAL TRACT | Orion-Yhtymä Oy (FI) | 1996-09-26 | — | — | WO | disclosed |