Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573559 | 0.87 | RAD52 (0.48) | TAS1R3TAS1R1CTSDRAD52SMARCA2 | |
| SCHEMBL7567962 | 0.85 | TERT (0.39) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7564172 | 0.85 | TAS1R3 (0.41) | TAS1R3TAS1R1PDE3BPDE3AMEN1 | |
| SCHEMBL7567229 | 0.84 | TAS1R3 (0.37) | TAS1R3TAS1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL7565911 | 0.84 | RAD52 (0.39) | TAS1R3TAS1R1RAD52MEN1KMT2A | |
| SCHEMBL7571929 | 0.84 | TAS1R3 (0.48) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7567278 | 0.83 | AOX1 (0.38) | TAS1R3TAS1R1MEN1KMT2AALDH1A1 | |
| SCHEMBL7566567 | 0.83 | RAD52 (0.47) | TAS1R3TAS1R1HPGDSCTSDPDE3B | |
| SCHEMBL7567197 | 0.83 | KDM4E (0.48) | TAS1R3TAS1R1HPGDSMEN1KMT2A | |
| SCHEMBL7564805 | 0.83 | KDM4E (0.49) | TAS1R3TAS1R1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |