Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564172 | 0.88 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2CD38AOX1 | |
| SCHEMBL7567229 | 0.87 | TAS1R3 (0.37) | PARP1TAS1R3TAS1R1TAS1R2CD38 | |
| SCHEMBL7565911 | 0.87 | RAD52 (0.39) | PARP1TAS1R3TAS1R1TAS1R2CD38 | |
| SCHEMBL7571929 | 0.87 | TAS1R3 (0.48) | PARP1TAS1R3TAS1R1TAS1R2CD38 | |
| SCHEMBL7567278 | 0.86 | AOX1 (0.38) | PARP1TAS1R3TAS1R1TAS1R2AOX1 | |
| SCHEMBL7566344 | 0.86 | HDAC1 (0.48) | PARP1TAS1R3TAS1R1TAS1R2AOX1 | |
| SCHEMBL7566453 | 0.85 | CTSS (0.47) | PARP1TAS1R3TAS1R1TAS1R2CD38 | |
| SCHEMBL7565944 | 0.85 | TAS1R3 (0.46) | TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7564130 | 0.84 | MEN1 (0.40) | PARP1TAS1R3TAS1R1TAS1R2AOX1 | |
| SCHEMBL7573598 | 0.84 | TAS1R3 (0.38) | PARP1TAS1R3TAS1R1TAS1R2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |