Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566451 | 0.89 | ALDH1A1 (0.50) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7564724 | 0.83 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1PLK1LMNA | |
| SCHEMBL7566344 | 0.80 | HDAC1 (0.48) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7564998 | 0.77 | PKMYT1 (0.40) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7567052 | 0.77 | HDAC1 (0.39) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7572037 | 0.76 | ALDH1A1 (0.39) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7565766 | 0.74 | AOX1 (0.46) | TAS1R3TAS1R1ALDH1A1MAPTKDM4E | |
| SCHEMBL7567267 | 0.74 | RAD52 (0.44) | TAS1R3TAS1R1ALDH1A1GAAMAPT | |
| SCHEMBL7570917 | 0.74 | AOX1 (0.44) | ALDH1A1SMN1; SMN2HDAC1 | |
| Acridine SCHEMBL9614414 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |