Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562294 | 0.79 | FAAH (0.40) | ESR1ESR2TACR1SIGMAR1ALDH1A1 | |
| SCHEMBL6042429 | 0.79 | REN (0.36) | ESR1ESR2TACR1SLC6A3HTR2A | |
| SCHEMBL7566407 | 0.68 | DRD4 (0.42) | DRD4 | |
| SCHEMBL6042154 | 0.67 | REN (0.39) | HRH2ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7562261 | 0.65 | HCRTR1 (0.33) | TACR1ALDH1A1SLC6A4BCHEHCRTR1 | |
| SCHEMBL6044726 | 0.64 | MCHR1 (0.42) | SLC18A3TACR1ALDH1A1GAAMAPT | |
| SCHEMBL6044326 | 0.64 | MCHR1 (0.42) | SLC18A3TACR1ALDH1A1GAAMAPT | |
| SCHEMBL6042254 | 0.64 | MCHR1 (0.42) | SLC18A3TACR1ALDH1A1GAAMAPT | |
| SCHEMBL7562668 | 0.64 | MCHR1 (0.40) | SLC18A3TACR1ALDH1A1GAAMAPT | |
| SCHEMBL27279895 | 0.63 | TLR8 (0.45) | ALDH1A1MAPTRAB9ASMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |