SCHEMBL13699348

SCHEMBL13699348

OCCc1ccc(O)c(-n2nc3cc(Cl)c(Cl)cc3n2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
ALOX5 P09917 1/20 0.46
GAA P10253 1/20 0.46
BACE1 P56817 1/20 0.46
ALOX15 P16050 4/20 0.41
HPGD P15428 2/20 0.41
POLB P06746 2/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
IGF1R P08069 3/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CA2 P00918 1/20 0.34
AKR1B1 P15121 1/20 0.33
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700388 0.88 NPC1 (0.43) KDM4EALDH1A1MAPTALOX15HPGD
SCHEMBL7566832 0.87 MAPT (0.42) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL77763 0.85 LMNA (0.58) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL29517159 0.85 LMNA (0.58) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL28121238 0.84 NPC1 (0.42) KDM4EALDH1A1MAPTALOX15POLB
Hydrogen Sulfide SCHEMBL8439446 0.84 LMNA (0.56) KDM4EALDH1A1MAPTALOX5GAA
Ammonia Solution, Strong SCHEMBL8437470 0.84 LMNA (0.56) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL13700397 0.82 NPC1 (0.44) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL19302790 0.80 KDM4E (0.50) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL8649490 0.80 ALOX15 (0.42) KDM4EALDH1A1MAPTALOX5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed