Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309072 | 0.87 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL6308414 | 0.84 | MAOB (0.82) | MAOBMAOA | |
| SCHEMBL30067289 | 0.81 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL7215662 | 0.81 | MAOB (0.94) | MAOBMAOA | |
| SCHEMBL3501723 | 0.81 | MAOB (1.00) | MAOBMAOA | |
| SCHEMBL17332123 | 0.81 | MAOA (0.71) | MAOBMAOA | |
| SCHEMBL7222729 | 0.80 | MAOB (0.97) | MAOBMAOA | |
| SCHEMBL17332106 | 0.79 | MAOA (0.61) | MAOBMAOA | |
| SCHEMBL7184607 | 0.79 | MAOA (0.76) | MAOBMAOA | |
| SCHEMBL7218099 | 0.78 | MAOB (0.82) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058811-A1 | Naphthalene derivatives | CHENARD BERTRAND L (US) | 2002-05-16 | — | — | US | disclosed |
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058811-A1 | Naphthalene derivatives | HTR4, CNR1, CNR2 | MAOB 245/4885MAOA 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.