Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.41 |
| ▸ | FNTB | P49356 | 17/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 14/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | IL6 | P05231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498916 | 0.86 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7527024 | 0.86 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL3499840 | 0.85 | FNTA (0.58) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7588915 | 0.84 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL7168685 | 0.82 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL7168181 | 0.81 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL7566917 | 0.75 | BCAT2 (0.32) | — | |
| SCHEMBL7165817 | 0.74 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL7165194 | 0.71 | FNTA (0.35) | FNTAFNTBPGGT1B | |
| SCHEMBL7168702 | 0.71 | FNTA (0.37) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052380-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | disclosed |
| US-20020010184-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010184-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, ZMPSTE24 | FNTA 1/4885FNTB 2/4885PGGT1B 26/4885 |
| US-20020052380-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, GGPS1 | FNTA 1/4885FNTB 2/4885PGGT1B 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.