Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498917 | 0.87 | FFAR4 (0.34) | BCAT2BCAT1 | |
| Hydrochloric Acid SCHEMBL7527027 | 0.86 | FFAR4 (0.33) | BCAT2BCAT1 | |
| SCHEMBL3499837 | 0.85 | FNTA (0.44) | BCAT2BCAT1 | |
| Hydrochloric Acid SCHEMBL7588892 | 0.85 | FNTA (0.44) | BCAT2BCAT1 | |
| SCHEMBL6409378 | 0.82 | HTR1A (0.35) | — | |
| SCHEMBL6411741 | 0.82 | FNTA (0.34) | PRMT5WDR77GPR52 | |
| SCHEMBL7566909 | 0.75 | FNTA (0.41) | — | |
| SCHEMBL6409385 | 0.74 | PRMT5 (0.36) | PRMT5WDR77GPR52CACNA1H | |
| SCHEMBL6413460 | 0.72 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL6408970 | 0.72 | PRMT5 (0.31) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052380-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-05-02 | — | — | US | disclosed |
| US-20020010184-A1 | Inhibitors of prenyl-protein transferase | DINSMORE CHRISTOPHER J (US) | 2002-01-24 | — | — | US | disclosed |
| WO-2001060368-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010184-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, ZMPSTE24 | BCAT2 2130/4885BCAT1 1397/4885PRMT5 657/4885 |
| US-20020052380-A1 | Inhibitors of prenyl-protein transferase | FNTA, FNTB, GGPS1 | BCAT2 1045/4885BCAT1 334/4885PRMT5 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.