Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342696 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28342728 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL187513 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28881034 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28346028 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL28881707 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL9778150 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL21633726 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL21633789 | 1.00 | THRB (0.43) | THRBLMNACA2CA1MMP1 | |
| SCHEMBL185946 | 0.97 | THRB (0.39) | THRBLMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10750742-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-25 | — | — | US | claimed |
| US-20200048238-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-13 | — | — | US | claimed |
| EP-3606918-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2020-02-12 | — | — | EP | claimed |
| US-20190014783-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-17 | — | — | US | claimed |
| EP-3393245-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-10-31 | — | — | EP | claimed |
| WO-2018185187-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | claimed |
| WO-2017108569-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-29 | — | — | WO | claimed |
| CN-108463109-B | Pesticidally active pyrazole derivatives | 先正达参股股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-106892855-B | Novel compound, colored dispersion liquid, colored curable resin composition, color filter, and display device | 东友精细化工有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113031397-A | Colored curable resin composition, color filter, and display device | 东友精细化工有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-105732604-B | Compounds useful as dyes | 住友化学株式会社 | 2020-12-29 | — | — | CN | disclosed |
| US-10750742-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-25 | — | — | US | disclosed |
| US-20200048238-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-13 | — | — | US | disclosed |
| US-5817743-A | ANISOTROPICALLY ABSORBING MOLECULES, POLARIZED LIGHT | ALLIANT TECHSYSTEMS INC. (US) | 1998-10-06 | — | — | US | disclosed |
| US-5731405-A | POLYIMIDE COPOLYMER MADE FROM DIARYL KETONE TETRACARBOXYLIC DIANHYDRIDE, HYDROPHOBIC DIAMINE, AND ALICYCLIC TETRACARBOXYLIC ANHYDRIDE REACTANTS | ALLIANT TECHSYSTEMS INC. (US) | 1998-03-24 | — | — | US | disclosed |
| WO-1997037273-A2 | PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS | ALLIANT TECHSYSTEMS INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| EP-0536200-B1 | FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS | MINNESOTA MINING & MFG (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0536200-A1 | FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS. | MINNESOTA MINING & MFG (US) | 1993-04-14 | — | — | EP | disclosed |
| US-5087672-A | Lower birefringence and viscosity, increased hydrophobicity | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-02-11 | — | — | US | disclosed |
| WO-1991019773-A1 | FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190014783-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | THRB 3083/4885LMNA 2586/4885CA2 2063/4885 |
| US-10750742-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, CAT | THRB 3083/4885LMNA 2586/4885CA2 2063/4885 |
| US-20200048238-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | THRB 3040/4885LMNA 2318/4885CA2 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.