Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566170 | 0.83 | MAPK13 (0.32) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7566173 | 0.82 | MAPK13 (0.32) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7077185 | 0.81 | MAPK13 (0.37) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7082009 | 0.81 | ADRA2A (0.43) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7082583 | 0.77 | RAPGEF4 (0.35) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080443 | 0.73 | MAPK14 (0.37) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080366 | 0.71 | MAPK14 (0.45) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7082598 | 0.71 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080506 | 0.71 | ADRA2A (0.43) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7082231 | 0.70 | ALDH1A1 (0.41) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | claimed |