Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ACLY | P53396 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.56 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592771 | 0.83 | MEN1 (0.74) | KMT2AMEN1GAALMNAACLY | |
| SCHEMBL7567314 | 0.82 | NPSR1 (0.59) | KMT2AMEN1GAALMNAACLY | |
| SCHEMBL13011714 | 0.81 | KMT2A (0.74) | KMT2AMEN1GAAKDM4ELMNA | |
| SCHEMBL23200347 | 0.81 | KEAP1 (0.65) | KMT2AMEN1GAAKDM4ELMNA | |
| SCHEMBL7128448 | 0.81 | MEN1 (0.76) | KMT2AMEN1GAALMNAACLY | |
| SCHEMBL30926577 | 0.81 | MEN1 (0.76) | KMT2AMEN1GAALMNAACLY | |
| SCHEMBL27179805 | 0.80 | MEN1 (0.64) | KMT2AMEN1GAASLC20A2SLC20A1 | |
| SCHEMBL30927042 | 0.80 | MEN1 (0.64) | KMT2AMEN1GAASLC20A2SLC20A1 | |
| SCHEMBL1200684 | 0.80 | PARP14 (0.62) | KMT2AMEN1GAAKDM4ELMNA | |
| SCHEMBL15055485 | 0.80 | HSD17B2 (0.69) | KMT2AMEN1GAALMNAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |