Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625408 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2409497 | 0.81 | SLC6A3 (0.51) | MAPTHSP90AA1SLC6A3SLC6A4LMNA | |
| SCHEMBL6776132 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL1515716 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL31591207 | 0.80 | SLC6A3 (0.65) | ALDH1A1MAPTSMN1; SMN2SLC6A3SLC6A4 | |
| SCHEMBL31449995 | 0.80 | SLC6A4 (0.50) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL6985711 | 0.79 | SLC6A3 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL7597168 | 0.78 | SLC6A3 (0.51) | ALDH1A1HPGDMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL4722044 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2409281 | 0.77 | CYP4F2 (0.47) | ALDH1A1HPGDSLC6A3SLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | ALDH1A1 385/4885HPGD 943/4885MAPT 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.