Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515716 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL17152701 | 0.85 | MEN1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29641926 | 0.85 | MEN1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5033639 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTTSHR | |
| SCHEMBL11469172 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTTSHR | |
| SCHEMBL16709897 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17142154 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL17142153 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7458070 | 0.81 | KDM4E (0.53) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7458061 | 0.81 | KDM4E (0.53) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| EP-3325465-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| EP-3325465-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-11091501-B2 | Heterocyclic compounds as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20200270240-A1 | BENZOTHIAZOLE AND PYRIDOTHIAZOLE COMPOUNDS AS SUMO ACTIVATORS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2020-08-27 | — | — | US | disclosed |
| US-20200270240-A1 | BENZOTHIAZOLE AND PYRIDOTHIAZOLE COMPOUNDS AS SUMO ACTIVATORS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2020-08-27 | — | — | US | disclosed |
| CN-107428720-B | Substituted aminotriazoles as inhibitors of acid mammalian chitinase | 昂科艾伦迪治疗法股份公司 | 2020-06-30 | — | — | CN | disclosed |
| EP-3654975-A1 | BENZOTHIAZOLE AND PYRIDOTHIAZOLE COMPOUNDS AS SUMO ACTIVATORS | Icahn School of Medicine at Mount Sinai (US) | 2020-05-27 | — | — | EP | disclosed |
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |
| WO-2015067647-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067647-A1 | SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067646-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067646-A1 | SUBSTITUTED BENZAMIDES FOR TREATING ARTHROPODES | BAYER CROPSCIENCE AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| US-20150080364-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-20140073651-A1 | BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-03-13 | — | — | US | disclosed |
| EP-2678317-A1 | BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2014-01-01 | — | — | EP | disclosed |
| WO-2012114268-A1 | BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-08-30 | — | — | WO | disclosed |
| EP-1996590-A1 | SPIROINDOLINONE DERIVATIVES | F. Hoffmann-la Roche AG (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104664-A1 | SPIROINDOLINONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091501-B2 | Heterocyclic compounds as RSV inhibitors | SIRT1, FURIN, SIRT5 | ALDH1A1 721/4885MEN1 2857/4885KMT2A 2100/4885 |
| US-20200270240-A1 | BENZOTHIAZOLE AND PYRIDOTHIAZOLE COMPOUNDS AS SUMO ACTIVATORS | SUMO2, ATP2A2, ATP2A1 | ALDH1A1 3082/4885MEN1 4225/4885KMT2A 1387/4885 |
| US-20140073651-A1 | BENZAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | P2RX3, P2RX7, P2RX1 | ALDH1A1 1255/4885MEN1 3603/4885KMT2A 2816/4885 |
| US-20150080364-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | CPS1, FABP4, VHL | ALDH1A1 2586/4885MEN1 758/4885KMT2A 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.