Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409281 | 0.88 | CYP4F2 (0.47) | SLC6A3SLC6A4LMNAHPGDKMT2A | |
| SCHEMBL6624770 | 0.84 | SLC6A3 (0.46) | SLC6A3SLC6A4LMNAHPGDCA12 | |
| SCHEMBL6625089 | 0.82 | GABRA1 (0.49) | SLC6A3SLC6A4HPGDCA12CA2 | |
| SCHEMBL2409497 | 0.81 | SLC6A3 (0.51) | SLC6A3SLC6A4LMNAKMT2ATSHR | |
| SCHEMBL1515906 | 0.81 | CA12 (0.51) | SLC6A3SLC6A4LMNAHPGDCA12 | |
| SCHEMBL31591207 | 0.80 | SLC6A3 (0.65) | SLC6A3SLC6A4LMNACA2CA5A | |
| SCHEMBL31449995 | 0.80 | SLC6A4 (0.50) | SLC6A3SLC6A4LMNAHPGDKMT2A | |
| SCHEMBL6985711 | 0.79 | SLC6A3 (0.49) | SLC6A3SLC6A4LMNAHPGDKMT2A | |
| SCHEMBL7567378 | 0.78 | ALDH1A1 (0.48) | SLC6A3SLC6A4LMNAHPGDKMT2A | |
| SCHEMBL20806423 | 0.77 | SLC6A3 (0.54) | SLC6A3SLC6A4LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | SLC6A3 3408/4885SLC6A4 2771/4885LMNA 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.