Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546789 | 0.83 | ADORA3 (0.55) | ADORA3ALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL7400294 | 0.82 | MAPT (0.46) | ADORA3ALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL7508983 | 0.80 | HIF1A (0.52) | TSHRKMT2AMEN1POLBLMNA | |
| SCHEMBL7543877 | 0.79 | MAPT (0.49) | ADORA3ALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL7552681 | 0.78 | KDM4E (0.62) | ADORA3ALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL7391021 | 0.76 | ADORA3 (0.53) | ADORA3ALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL7445582 | 0.76 | HIF1A (0.59) | TSHRKMT2AMEN1POLBLMNA | |
| SCHEMBL7452042 | 0.75 | HIF1A (0.56) | TSHRKMT2AMEN1POLBLMNA | |
| SCHEMBL7593821 | 0.75 | ADORA3 (0.47) | ADORA3ALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL9280838 | 0.75 | HPGD (0.48) | ADORA3ALDH1A1HSD17B10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013812-A1 | USE OF SUBSTITUTED 1,4-DIHYDROPYRIDINE TO REDUCE INTRAOCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1995-05-26 | — | — | WO | claimed |