Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280838 | 0.89 | HPGD (0.48) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL7406051 | 0.88 | ADORA3 (0.53) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL7391021 | 0.87 | ADORA3 (0.53) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL7543877 | 0.83 | MAPT (0.49) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL9825000 | 0.82 | ADORA3 (0.54) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL7400294 | 0.81 | MAPT (0.46) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL11780011 | 0.81 | ADORA3 (0.60) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL10488517 | 0.81 | ADORA3 (0.53) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL10692951 | 0.81 | ADORA3 (0.53) | ADORA3MAPTHIF1AKMT2ACYP1A2 | |
| SCHEMBL9789816 | 0.81 | RAB9A (0.55) | ADORA3MAPTHIF1AKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013812-A1 | USE OF SUBSTITUTED 1,4-DIHYDROPYRIDINE TO REDUCE INTRAOCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1995-05-26 | — | — | WO | claimed |
| US-5378718-A | Cardiovascular activity, hypotensive | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-03 | — | — | US | disclosed |