Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400294 | 0.92 | MAPT (0.46) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7593821 | 0.89 | ADORA3 (0.47) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7365604 | 0.88 | MAPT (0.52) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7391021 | 0.87 | ADORA3 (0.53) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7543877 | 0.83 | MAPT (0.49) | HPGDMAPTLMNAADORA3CYP1A2 | |
| SCHEMBL7390505 | 0.80 | MAPT (0.56) | MAPTHSD17B10KDM4ETSHRPOLB | |
| SCHEMBL7361981 | 0.79 | CYP2C9 (0.46) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7508983 | 0.78 | HIF1A (0.52) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7406051 | 0.76 | ADORA3 (0.53) | HPGDMAPTLMNASMN1; SMN2ADORA3 | |
| SCHEMBL7567774 | 0.75 | ADORA3 (0.51) | HPGDMAPTLMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378718-A | Cardiovascular activity, hypotensive | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-03 | — | — | US | disclosed |