Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801085 | 0.81 | CA2 (0.63) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL16300320 | 0.81 | CA2 (0.63) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11099393 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14380840 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL20874488 | 0.76 | POLB (0.46) | SMN1; SMN2MEN1KMT2APMP22ATM | |
| SCHEMBL11413367 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL20874474 | 0.74 | ALDH1A1 (0.54) | KMT2APMP22ATML3MBTL1CA7 | |
| SCHEMBL3217835 | 0.74 | HTT (0.51) | SMN1; SMN2CYP1A2CYP2D6CYP2C9L3MBTL1 | |
| SCHEMBL4590876 | 0.74 | SOAT1 (0.53) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL7858623 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229019-A1 | PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLIC ENAMINONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |